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Anti-Aspartate Aminotransferase Antibody (3P649) 是一种 Rabbit 抗体,靶向 Aspartate Aminotransferase。Anti-Aspartate Aminotransferase Antibody (3P649) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。
Anti-Aspartate Aminotransferase Antibody (3P649) 是一种 Rabbit 抗体,靶向 Aspartate Aminotransferase。Anti-Aspartate Aminotransferase Antibody (3P649) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,380 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-Aspartate Aminotransferase Antibody (3P649) is a Rabbit antibody targeting Aspartate Aminotransferase. Anti-Aspartate Aminotransferase Antibody (3P649) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF. |
| Ig Type | IgG |
| 克隆号 | 3P649 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIFFCMICC/IF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Aspartate Aminotransferase [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate-dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. |
| 免疫原 | A synthesized peptide: human GOT1 |
| 抗原种属 | Human |
| 基因名称 | GOT1 |
| 基因ID | |
| 蛋白名称 | Aspartate aminotransferase, cytoplasmic |
| Uniprot ID | |
| 功能 | Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. |
| 分子量 | Theoretical: 46 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |