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Perfluorohexane (AF-0150) 是一种基于全氟化碳 (PFC) 的微泡制剂,是超声造影剂,具有发育毒性,可通过 NMDA 受体介导的 PKC-ERK/AMPK 信号通路诱导记忆障碍和神经蛋白下调。Perfluorohexane 干扰小鼠的发情周期、排卵率、卵母细胞通讯和钙稳态。
Perfluorohexane (AF-0150) 是一种基于全氟化碳 (PFC) 的微泡制剂,是超声造影剂,具有发育毒性,可通过 NMDA 受体介导的 PKC-ERK/AMPK 信号通路诱导记忆障碍和神经蛋白下调。Perfluorohexane 干扰小鼠的发情周期、排卵率、卵母细胞通讯和钙稳态。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 g | ¥ 185 | 现货 | |
10 g | ¥ 297 | 现货 |
产品描述 | Perfluorohexane (AF-0150), a perfluorocarbon (PFC)-based microbubble formulation, is an ultrasound contrast agent with developmental toxicity that induces memory deficits and neuroprotein downregulation through the NMDA receptor-mediated PKC-ERK/AMPK signaling pathway.Perfluorohexane interferes with estrous cycle, ovulation rate in mice, Perfluorohexane interferes with estrous cycle, ovulation rate, oocyte communication and calcium homeostasis in mice. |
别名 | AF-0150, AF0150 |
分子量 | 338.04 |
分子式 | C6F14 |
CAS No. | 355-42-0 |
Smiles | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F |
密度 | 1.669 g/cm3 at 25℃ (lit.) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 80 mg/mL (236.66 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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