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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL-23 Antibody (8I736)

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货号 TMAB-07640

Anti-IL-23 Antibody (8I736) 是一种 Rabbit 抗体，靶向 IL-23。Anti-IL-23 Antibody (8I736) 可用于 WB。

Anti-IL-23 Antibody (8I736)

Anti-IL-23 Antibody (8I736)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07640

Anti-IL-23 Antibody (8I736) 是一种 Rabbit 抗体，靶向 IL-23。Anti-IL-23 Antibody (8I736) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-23 Antibody (8I736) is a Rabbit antibody targeting IL-23. Anti-IL-23 Antibody (8I736) can be used in WB.
Ig Type
IgG
克隆号
8I736
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted. Secreted upon association with IL12B.
组织特异性Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.
抗原信息
免疫原
A synthesized peptide: human IL 23A
抗原种属
Human
基因名称
Il23a
基因ID
51561
蛋白名称
Interleukin-23 subunit alpha
Uniprot ID
Q9NPF7
功能
Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
化学信息
分子量Theoretical: 21 kDa. Actual: 21 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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