Anti-Osteoprotegerin Polyclonal Antibody is a Rabbit antibody targeting Osteoprotegerin. Anti-Osteoprotegerin Polyclonal Antibody can be used in IF,IHC-Fr,WB.

IgG

Human,Mouse,Rat (predicted:Dog,Cow)

1. Sample:
Heart (Mouse) Lysate at 40 μg
Kidney (Mouse) Lysate at 40 μg
Liver (Mouse) Lysate at 40 μg
Primary: Anti-OPg (TMAB-01300) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kDa
Observed band size: 50 kDa
2. Sample:
Lane 1: Raji (Human) Cell Lysate at 30 μg
Lane 2: U251 (Human) Cell Lysate at 30 μg
Primary: Anti-OPG (TMAB-01300) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa

WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500

Polyclonal

KLH conjugated synthetic peptide: human OPG

Human

TNFRSF11B

Tumor necrosis factor receptor superfamily member 11B

Inflammatory mediators,Blood,Bone,TNF Superfamily,Obesity,Bone,TNF

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.