规格

价格

库存

数量

5 μg

¥ 428

6-8日内发货

10 μg

¥ 683

6-8日内发货

20 μg

¥ 1,130

5日内发货

50 μg

¥ 2,270

5日内发货

100 μg

¥ 4,430

5日内发货

200 μg

¥ 6,480

5日内发货

500 μg

¥ 12,800

5日内发货

1 mg

¥ 25,500

5日内发货

生物活性

产品描述	IL-22RA1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q8N6P7.
生物活性	Immobilized Human IL-22R alpha 1, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-IL-22R alpha 1 Antibody, hFc Tag with the EC50 of 6.4 ng/ml determined by ELISA (QC Test).
研究背景	IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q8N6P7
蛋白构建	His16-Thr228
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	IL22R1, IL22R, CRF2-9
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	25.67 kDa (predicted); 35-45 kDa (reducing contition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

IL-22RA1 Protein, Human, Recombinant (His)

IL-22RA1 Protein, Human, Recombinant (His)

产品介绍

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