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Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3
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还可以产品编号 TMAB-10529
Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-Cofilin (Ser3)。Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3
Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3
一键复制产品信息 还可以产品编号 TMAB-10529
Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-Cofilin (Ser3)。Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-Cofilin (Ser3). Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human,Pig,Cow,Horse,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide. |
| 组织特异性 | Widely distributed in various tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human Cofilin around the phosphorylation site of Ser3 |
| 抗原种属 | Human |
| 基因名称 | CFL1 |
| 基因ID | |
| 蛋白名称 | Cofilin-1 |
| Uniprot ID | |
| 功能 | Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. |
| 分子量 | Theoretical: 18 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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