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Anti-MICA Antibody-PE (3K607)
还可以产品编号 TMAY-02316P
Anti-MICA Antibody-PE (3K607) 是一种 PE-conjugated Mouse 抗体，靶向 MICA。Anti-MICA Antibody-PE (3K607) 可用于 FCM。
Anti-MICA Antibody-PE (3K607)
Anti-MICA Antibody-PE (3K607)
还可以产品编号 TMAY-02316P
Anti-MICA Antibody-PE (3K607) 是一种 PE-conjugated Mouse 抗体，靶向 MICA。Anti-MICA Antibody-PE (3K607) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MICA Antibody-PE (3K607) is a PE-conjugated Mouse antibody targeting MICA. Anti-MICA Antibody-PE (3K607) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3K607 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-MICA reactivity on HeLa cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICA (rh MICA; TMPY-02053; AAH16929.1; Met 1-Gln 308) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human MICA protein (TMPY-02053) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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