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Anti-PSME1 Antibody (3F619)
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产品编号 TMAY-02764
别名 REGα, REGalpha, proteasome (prosome, macropain) activator subunit 1 (PA28 α), proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), PA28α, PA28alpha, PA28A, IFI5111
Anti-PSME1 Antibody (3F619) 是一种 Rabbit 抗体，靶向 PSME1。Anti-PSME1 Antibody (3F619) 可用于 WB,ELISA。
Anti-PSME1 Antibody (3F619)
Anti-PSME1 Antibody (3F619)
还可以产品编号 TMAY-02764 别名 REGα, REGalpha, proteasome (prosome, macropain) activator subunit 1 (PA28 α), proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), PA28α, PA28alpha, PA28A, IFI5111
Anti-PSME1 Antibody (3F619) 是一种 Rabbit 抗体，靶向 PSME1。Anti-PSME1 Antibody (3F619) 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-PSME1 Antibody (3F619) is a Rabbit antibody targeting PSME1. Anti-PSME1 Antibody (3F619) can be used in WB,ELISA. |
| 别名 | REGα, REGalpha, proteasome (prosome, macropain) activator subunit 1 (PA28 α), proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), PA28α, PA28alpha, PA28A, IFI5111 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3F619 |
| 交叉反应 | Human |
| 验证活性 | Anti-PSME1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: HL60 Whole Cell Lysate. -Lane B: HeLa Whole Cell Lysate. -Lane C: MCF7 Whole Cell Lysate. -Lane D: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:29 kDa. -Observed band size:33 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PA28A / PSME1 (rh PA28A / PSME1; TMPY-03612; Q06323; Met1-Tyr249). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME1 gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human PA28A / PSME1 Protein (TMPY-03612) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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