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MCP-1/CCL2 Protein, Human, Recombinant (His)

产品编号 TMPY-00118

别名: SCYA2, HC11, MCAF, HSMCR30, MCP-1, MCP1, GDCF-2, SMC-CF, chemokine (C-C motif) ligand 2

MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.

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TargetMol

MCP-1/CCL2 Protein, Human, Recombinant (His)

规格	价格/CNY		货期	数量
50 μg	￥ 2,430		现货
100 μg	￥ 4,090		5日内发货
200 μg	￥ 6,860		5日内发货
500 μg	￥ 13,540		5日内发货

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生物活性

技术参数

产品性质

参考文献

生物活性	Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with mouse CCR2. The ED50 for this effect is 20-200 ng/mL.
产品描述	MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.

种属	Human
表达系统	P. pastoris (Yeast)
标签	C-His
蛋白编号	P13500
别名	SCYA2, HC11, MCAF, HSMCR30, MCP-1, MCP1, GDCF-2, SMC-CF, chemokine (C-C motif) ligand 2
蛋白构建	The Human CCL2 (NP_002973.1) (Gln24-Thr99) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	10.1 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

参考文献

1. Vásquez-Loarte T, Trubnykova M, Guio H. Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model. BMC Genetics. 2015;16:128.

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Keywords

MCP-1/CCL2 Protein, Human, Recombinant (His) SCYA2 HC 11 HC11 MCAF HSMCR-30 GDCF2 HSMCR30 HC-11 SCYA 2 MCP 1 HSMCR 30 GDCF 2 MCP-1 SCYA-2 MCP1 GDCF-2 SMC-CF chemokine (C-C motif) ligand 2 recombinant recombinant-proteins proteins protein

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