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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Cytokeratin 2 Polyclonal Antibody

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货号 TMAB-04948

Anti-Cytokeratin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Cytokeratin 2。Anti-Cytokeratin 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Cytokeratin 2 Polyclonal Antibody

Anti-Cytokeratin 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04948

Anti-Cytokeratin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Cytokeratin 2。Anti-Cytokeratin 2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Cytokeratin 2 Polyclonal Antibody is a Rabbit antibody targeting Cytokeratin 2. Anti-Cytokeratin 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Keratins are a group of water-insoluble proteins that form monofilaments, a class of intermediate filament. These filaments form part of the cytoskeletal complex in epidermis and in most other epithelial tissues. Nineteen human epithelial keratins are resolved with two-dimensional gels electrophoresis (1). These can be divided into acid (pI 6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45 and 40 kD. The basic keratins have molecular weights of 65-67, 64, 59, 58, 56 and 52kD. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state (2-4). The 56.5/65-67kD pair is present in keratinized (differentiated) epidermis. The 55/64kD pair is characteristic of normal (corneal-type) epithelial differentiation (1,2). The 51/59kD pair is characteristic of the stratified squamous epithelial of internal organism such as esophagus and tongue (1,3). The 51/58kD pair is a keratinocyte marker; this pair is present in almost all stratified epithelia irrespective of the state of cellular stratification (1,2). The 48/56kD pair is characteristic of hyperproliferative (de-differentiated) keratinocytes (1,5). The 45/52kD pair and to a lesser extent, the 46/54kD pair are characteristic of simple epithelia (1). The 40kD keratin is present in most epithelia except adult epidermis (1).
抗原信息
免疫原
KLH conjugated synthetic peptide: human CK2
抗原种属
Human
基因名称
KRT76
基因ID
51350
蛋白名称
Keratin, type II cytoskeletal 2 oral
Uniprot ID
Q01546
功能
Probably contributes to terminal cornification.
化学信息
分子量Theoretical: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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