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Anti-CXADR Monoclonal Antibody-Biotin

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产品编号 TMAZ-0258B

别名 HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor

Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-CXADR Monoclonal Antibody-Biotin

Anti-CXADR Monoclonal Antibody-Biotin

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产品编号 TMAZ-0258B 别名 HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor

Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
25 μg
¥ 1,250
7日内发货
50 μg
¥ 1,500
7日内发货
100 μg
¥ 2,099
7日内发货
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产品介绍

生物活性
产品描述
Anti-CXADR Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-Biotin can be used in ELISA,FCM.
别名HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of CXADR overexpressed 463F cells with TMAZ-0258B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CXADR protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair|(Microbial infection) Acts as a receptor for adenovirus type C|(Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6
偶联与修饰
偶联
Biotin
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
CXADR
抗原种属
Human
基因ID
1525
Uniprot ID
P78310
研究领域
Other Functions
化学信息
分子量150 kDa
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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