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IL-T3 Protein, Human, Recombinant (His)

IL-T3 Protein, Human, Recombinant (His)

产品编号 TMPY-04650
别名: CD85K, leukocyte immunoglobulin like receptor B4, ILT-3, LIR5, ILT3, LIR-5

IL-T3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q8NHJ6.

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IL-T3 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
50 μg ¥ 3,170 现货
100 μg ¥ 5,610 5日内发货
200 μg ¥ 9,920 5日内发货
500 μg ¥ 20,980 5日内发货
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产品目录号及名称: IL-T3 Protein, Human, Recombinant (His) (TMPY-04650)
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生物活性
技术参数
产品性质
生物活性 Loaded Human ILT3 alpha Protein, His Tag on AR2G Biosensor, can bind Rhesus Angiopoietin-like 7 Protein, His Tag with an affinity constant of 68.94nM as determined in BLI assay (Routinely tested).
产品描述 IL-T3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q8NHJ6.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q8NHJ6
别名 CD85K, leukocyte immunoglobulin like receptor B4, ILT-3, LIR5, ILT3, LIR-5
蛋白构建 The Human LILRB4 (NP_001265357.2) (Met1-Glu259) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度 ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

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分子量 27.7 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.

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Keywords

IL-T3 Protein, Human, Recombinant (His) CD85K leukocyte immunoglobulin like receptor B4 ILT 3 ILT-3 LIR 5 LIR5 ILT3 LIR-5 recombinant recombinant-proteins proteins protein

 

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