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Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SNAIL+SLUG (Ser246)。Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SNAIL+SLUG (Ser246)。Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAIL+SLUG (Ser246). Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. |
| 组织特异性 | Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human SNAIL around the phosphorylation site of Ser246 |
| 抗原种属 | Human |
| 基因名称 | SNAI1 |
| 基因ID | |
| 蛋白名称 | Zinc finger protein SNAI1 |
| Uniprot ID | |
| 功能 | Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. |
| 分子量 | Theoretical: 32 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |