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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Arginase II Polyclonal Antibody

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货号 TMAB-02816

Anti-Arginase II Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Arginase II。Anti-Arginase II Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-Arginase II Polyclonal Antibody

Anti-Arginase II Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02816

Anti-Arginase II Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Arginase II。Anti-Arginase II Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Arginase II Polyclonal Antibody is a Rabbit antibody targeting Arginase II. Anti-Arginase II Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Cow,Rabbit)
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea (1). The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster (2-4). Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location (5,6). Specifically, arginase II localizes to the mitochondria (5,6). Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver (5,6). The human arginase II gene, which maps to chromosome 14q24.1, encodes a 354 amino acid protein (3,5-7). In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence (5,6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Arginase II
抗原种属
Human
基因名称
ARG2
基因ID
384
蛋白名称
Arginase-2, mitochondrial
Uniprot ID
P78540
功能
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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