Name: CART Protein, Human, Recombinant (mFc)
Brand: TargetMol
SKU: TMPY-03806
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 493

6-8日内发货

10 μg

¥ 790

6-8日内发货

20 μg

¥ 1,330

5日内发货

50 μg

¥ 2,580

5日内发货

100 μg

¥ 5,170

5日内发货

生物活性

产品描述	CART Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36.3 kDa and the accession number is Q16568.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	In RNAseq data from human islet donors, CARTPT expression levels correlated with insulin, exocytosis genes and key beta-cell transcription factors. Insufficient insulin release and hyperglucagonaemia are culprits in type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART, encoded by Cartpt) affects islet hormone secretion and beta cell survival in vitro in rats, and Cart (-/-) mice have diminished insulin secretion. Established a potential role for cocaine and amphetamine regulated transcript (CARTPT) in dominant follicle selection in cattle. CARTPT expression is elevated in subordinate versus dominant follicles, and treatment with the mature form of the CARTPT peptide (CART) decreases follicle-stimulating hormone (FSH)-stimulated granulosa cell estradiol production in vitro and follicular fluid estradiol and granulosa cell CYP19A1 mRNA in vivo.
种属	Human
表达系统	HEK293 Cells
标签	C-mFc
蛋白编号	Q16568
蛋白构建	A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with the Fc region of mouse IgG1 at the C-terminus. Predicted N terminal: Gln 28
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	CART prepropeptide, CART
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	36.3 kDa (predicted); 37 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CART Protein, Human, Recombinant (mFc)

CART Protein, Human, Recombinant (mFc)

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