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Anti-TRXR1/TXNRD1 Antibody (8M522) 是一种 Rabbit 抗体,靶向 TRXR1/TXNRD1。Anti-TRXR1/TXNRD1 Antibody (8M522) 可用于 WB,ICC,IHC,IP,FCM。
Anti-TRXR1/TXNRD1 Antibody (8M522) 是一种 Rabbit 抗体,靶向 TRXR1/TXNRD1。Anti-TRXR1/TXNRD1 Antibody (8M522) 可用于 WB,ICC,IHC,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-TRXR1/TXNRD1 Antibody (8M522) is a Rabbit antibody targeting TRXR1/TXNRD1. Anti-TRXR1/TXNRD1 Antibody (8M522) can be used in WB,ICC,IHC,IP,FCM. |
别名 | TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of TXNRD1 on Hela (1) and human liver tissue lysate (2) using anti-TXNRD1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TXNRD1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse testes tissue using anti-TXNRD1 antibody. Counter stained with hematoxylin. 4. ICC staining TXNRD1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of SH-SY5Y cells with TXNRD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx reductases (TrxR1 and TrxR2) are ubiquitous Ly noble flavoproteins that catalyze the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. Mammalian Trx reductases are a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val- Asn-Val-Gly-Cys. TrxR1 and TrxR2 are also involved in the prevention of oxidative stress. Inhibition of TrxR activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 55 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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