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Anti-REG4 Antibody (8R747)

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产品编号 TMAY-01729

Anti-REG4 Antibody (8R747) 是一种 Rabbit 抗体,靶向 REG4。Anti-REG4 Antibody (8R747) 可用于 IHC-P。

Anti-REG4 Antibody (8R747)

Anti-REG4 Antibody (8R747)

Rating icon 还可以
产品编号 TMAY-01729

Anti-REG4 Antibody (8R747) 是一种 Rabbit 抗体,靶向 REG4。Anti-REG4 Antibody (8R747) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-REG4 Antibody (8R747) is a Rabbit antibody targeting REG4. Anti-REG4 Antibody (8R747) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
8R747
交叉反应
Human
验证活性
1. Immunochemical staining of human REG4 in human colon with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of human REG4 in human small intestine with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human REG4 (rh REG4; TMPY-01352; NP_001152824.1; Met 1-Pro 158).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human REG4 Protein (TMPY-01352)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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