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顶部生物活性储存和溶解信息计算器

Anti-PIWIL1 Antibody (9H748)

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Anti-PIWIL1 Antibody (9H748)
产品编号 TMAC-03305
别名 PIWL1_HUMAN, Piwi-like protein 1, PIWIL 1, Piwi like 1 (drosophila), Piwi like 1, Piwi homolog, Piwi (Drosophila) like 1, PIWI, MIWI, HIWI

Anti-PIWIL1 Antibody (9H748) 是一种 Rabbit 抗体，靶向 PIWIL1。Anti-PIWIL1 Antibody (9H748) 可用于 WB,IHC。

Anti-PIWIL1 Antibody (9H748)

Anti-PIWIL1 Antibody (9H748)

Rating icon 还可以
Anti-PIWIL1 Antibody (9H748)
产品编号 TMAC-03305 别名 PIWL1_HUMAN, Piwi-like protein 1, PIWIL 1, Piwi like 1 (drosophila), Piwi like 1, Piwi homolog, Piwi (Drosophila) like 1, PIWI, MIWI, HIWI

Anti-PIWIL1 Antibody (9H748) 是一种 Rabbit 抗体，靶向 PIWIL1。Anti-PIWIL1 Antibody (9H748) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIWIL1 Antibody (9H748) is a Rabbit antibody targeting PIWIL1. Anti-PIWIL1 Antibody (9H748) can be used in WB,IHC.
别名PIWL1_HUMAN, Piwi-like protein 1, PIWIL 1, Piwi like 1 (drosophila), Piwi like 1, Piwi homolog, Piwi (Drosophila) like 1, PIWI, MIWI, HIWI
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PIWIL1 on mouse testis tissue lysate using anti-PIWIL1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-PIWIL1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PIWIL1 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Endoribonuclease that plays a central role in postnatal germ cells by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Strongly prefers a uridine in the first position of their guide (g1U preference, also named 1U-bias). Not involved in the piRNA amplification loop, also named ping-pong amplification cycle. Acts as an endoribonuclease that cleaves transposon messenger RNAs. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability. Required to sequester RNF8 in the cytoplasm until late spermatogenesis; RNF8 being released upon ubiquitination and degradation of PIWIL1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q96J94
化学信息
分子量Theoretical: 98 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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