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Anti-FSTL3 Antibody (6R403)
还可以产品编号 TMAY-03044
Anti-FSTL3 Antibody (6R403) 是一种 Rabbit 抗体，靶向 FSTL3。Anti-FSTL3 Antibody (6R403) 可用于 ELISA。
Anti-FSTL3 Antibody (6R403)
Anti-FSTL3 Antibody (6R403)
还可以产品编号 TMAY-03044
Anti-FSTL3 Antibody (6R403) 是一种 Rabbit 抗体，靶向 FSTL3。Anti-FSTL3 Antibody (6R403) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-FSTL3 Antibody (6R403) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (6R403) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6R403 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FLRG / Fstl3 (rM FLRG / Fstl3; TMPY-00975; NP_113557.1; Met 1-Val 256). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 of FLRG/Fstl3 or the nuclear form of FLRG/Fstl3 is probably involved in transcriptional regulation via interaction with MLLT10. Modulation of activin and other TGFβ superfamily signaling is the primary mechanism of action for both follistatin (FS) and FS-like 3 (FSTL-3). FLRG/Fstl3 is likely to be a local regulator of activin action in gonadal development and gametogenesis and, further, that activin appears to have important actions in gonadal development and function that are critical for normal reproduction. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse FLRG protein (TMPY-00975) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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