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Anti-FSTL3 Antibody (6R403)

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Anti-FSTL3 Antibody (6R403)
产品编号 TMAY-03044
别名 follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik

Anti-FSTL3 Antibody (6R403) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (6R403) 可用于 ELISA。

Anti-FSTL3 Antibody (6R403)
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Anti-FSTL3 Antibody (6R403)

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Anti-FSTL3 Antibody (6R403)
产品编号 TMAY-03044 别名 follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik

Anti-FSTL3 Antibody (6R403) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (6R403) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-FSTL3 Antibody (6R403) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (6R403) can be used in ELISA.
别名follistatin-like 3 (secreted glycoprotein), Flrg, E030038F23Rik
Ig Type
Rabbit IgG
克隆号
6R403
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FLRG / Fstl3 (rM FLRG / Fstl3; TMPY-00975; NP_113557.1; Met 1-Val 256).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Follistatin-like 3 (FLRG/Fstl3) is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis. FLRG/Fstl3 is a recently described member of the FST family having an overall structure and activity profile similar to that of FST, including binding and neutralization of activin. FLRG/Fstl3 is expressed in a wide range of adult tissues, not detected in hematopoietic cells except in patients with a B cell chronic leukemia and a translocation. Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 of FLRG/Fstl3 or the nuclear form of FLRG/Fstl3 is probably involved in transcriptional regulation via interaction with MLLT10. Modulation of activin and other TGFβ superfamily signaling is the primary mechanism of action for both follistatin (FS) and FS-like 3 (FSTL-3). FLRG/Fstl3 is likely to be a local regulator of activin action in gonadal development and gametogenesis and, further, that activin appears to have important actions in gonadal development and function that are critical for normal reproduction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse FLRG protein (TMPY-00975)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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