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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD314 Monoclonal Antibody (2G841)

Synonyms: NKG2-D, NKG2D, KLRK1, KLR, D12S2489E
货号 TMAT-0370 一键复制产品信息
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Anti-CD314 Monoclonal Antibody (2G841) 是一种 Mouse 抗体，靶向 CD314。Anti-CD314 Monoclonal Antibody (2G841) 可用于 WB,FCM。

Anti-CD314 Monoclonal Antibody (2G841)

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货号 TMAT-0370

别名 NKG2-D, NKG2D, KLRK1, KLR, D12S2489E

Anti-CD314 Monoclonal Antibody (2G841) 是一种 Mouse 抗体，靶向 CD314。Anti-CD314 Monoclonal Antibody (2G841) 可用于 WB,FCM。

Anti-CD314 Monoclonal Antibody (2G841)
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产品介绍

生物活性
产品描述
Anti-CD314 Monoclonal Antibody (2G841) is a Mouse antibody targeting CD314. Anti-CD314 Monoclonal Antibody (2G841) can be used in WB,FCM.
别名
NKG2-D, NKG2D, KLRK1, KLR, D12S2489E
Ig Type
IgG2a
克隆号
2G841
反应种属
Human, Rat
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD314 (AA: extra 73-216) expressed in E. Coli.
抗原种属
Human
基因名称
KLRK1
基因ID
22914
蛋白名称
NKG2-D type II integral membrane protein
Uniprot ID
P26718
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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