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Anti-Periostin Antibody (2Y740)

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货号 TMAB-10191

Anti-Periostin Antibody (2Y740) 是一种 Rabbit 抗体,靶向 Periostin。Anti-Periostin Antibody (2Y740) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Periostin Antibody (2Y740)

Anti-Periostin Antibody (2Y740)

一键复制产品信息
Rating icon 还可以
货号 TMAB-10191

Anti-Periostin Antibody (2Y740) 是一种 Rabbit 抗体,靶向 Periostin。Anti-Periostin Antibody (2Y740) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-Periostin Antibody (2Y740) is a Rabbit antibody targeting Periostin. Anti-Periostin Antibody (2Y740) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
2Y740
反应种属
Human
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
抗原信息
免疫原
A synthesized peptide: human Periostin
抗原种属
Human
基因名称
POSTN
基因ID
蛋白名称
Periostin
Uniprot ID
功能
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
化学信息
分子量Theoretical: 100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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