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Anti-Periostin Antibody (2Y740) 是一种 Rabbit 抗体,靶向 Periostin。Anti-Periostin Antibody (2Y740) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-Periostin Antibody (2Y740) 是一种 Rabbit 抗体,靶向 Periostin。Anti-Periostin Antibody (2Y740) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-Periostin Antibody (2Y740) is a Rabbit antibody targeting Periostin. Anti-Periostin Antibody (2Y740) can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 2Y740 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors. |
| 免疫原 | A synthesized peptide: human Periostin |
| 抗原种属 | Human |
| 基因名称 | POSTN |
| 基因ID | |
| 蛋白名称 | Periostin |
| Uniprot ID | |
| 功能 | Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. |
| 分子量 | Theoretical: 100 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |