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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-USP3 Polyclonal Antibody

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货号 TMAB-14024

Anti-USP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP3。Anti-USP3 Polyclonal Antibody 可用于 WB。

Anti-USP3 Polyclonal Antibody

Anti-USP3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14024

Anti-USP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP3。Anti-USP3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-USP3 Polyclonal Antibody is a Rabbit antibody targeting USP3. Anti-USP3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin.
组织特异性Expressed in all tissues examined, with strongest expression in pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP3 (ubiquitin specific peptidase 3), also known as UBP or SIH003, is a 520 amino acid protein that contains one UBP-type zinc finger and belongs to the peptidase C19 family. Expressed ubiquitously with highest levels present in pancreas, USP3 catalyzes the conversion of a ubiquitin C-terminal thioester to a free ubiquitin and a thiol. The gene encoding USP3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human USP3
抗原种属
Human
基因名称
USP3
基因ID
9960
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 3
Uniprot ID
Q9Y6I4
功能
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
化学信息
分子量Theoretical: 59 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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