购物车
- 全部删除
您的购物车当前为空
Anti-Phospho-PTK2 (Tyr397) Antibody (5N156)
还可以产品编号 TMAH-00950
别名 PTK2 protein tyrosine kinase 2, Protein tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, Phospho-PTK2 (Y397), p125FAK, FRNK, Focal adhesion kinase related nonkinase, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase 1, Focal adhesion Kinase, FAK1, FAK related non kinase polypeptide, FADK 1, FADK
Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) 是一种抗体，靶向 Phospho-PTK2 (Tyr397)。Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) 可用于 ELISA, WB。
Anti-Phospho-PTK2 (Tyr397) Antibody (5N156)
Anti-Phospho-PTK2 (Tyr397) Antibody (5N156)
还可以产品编号 TMAH-00950 别名 PTK2 protein tyrosine kinase 2, Protein tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, Phospho-PTK2 (Y397), p125FAK, FRNK, Focal adhesion kinase related nonkinase, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase 1, Focal adhesion Kinase, FAK1, FAK related non kinase polypeptide, FADK 1, FADK
Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) 是一种抗体，靶向 Phospho-PTK2 (Tyr397)。Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) is an antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) can be used in ELISA, WB. |
| 别名 | PTK2 protein tyrosine kinase 2, Protein tyrosine kinase 2, Protein phosphatase 1 regulatory subunit 71, PPP1R71, pp125FAK, Phospho-PTK2 (Y397), p125FAK, FRNK, Focal adhesion kinase related nonkinase, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase 1, Focal adhesion Kinase, FAK1, FAK related non kinase polypeptide, FADK 1, FADK |
| Ig Type | Rabbit IgG |
| 克隆号 | 5N156 |
| 交叉反应 | Human |
| 验证活性 | Western Blot -Positive WB detected in Hela whole cell lysate -All lanes Phospho-PTK2 antibody at 3.05μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 119 KDa -Observed band size: 119 KDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Note=Constituent of focal adhesions. Detected at microtubules. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL. Promotes phosphorylation of PXN and STAT1; most likely PXN and STAT1 are phosphorylated by a SRC family kinase that is recruited to autophosphorylated PTK2/FAK1, rather than by PTK2/FAK1 itself. Promotes phosphorylation of BCAR1; GIT2 and SHC1; this requires both SRC and PTK2/FAK1. Promotes phosphorylation of BMX and PIK3R1. Isoform 6 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling. Its enhanced expression can attenuate the nuclear accumulation of LPXN and limit its ability to enhance serum response factor (SRF)-dependent gene transcription. Isoform 6 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling. Its enhanced expression can attenuate the nuclear accumulation of LPXN and limit its ability to enhance serum response factor (SRF)-dependent gene transcription. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Phospho-PTK2 (Y397) |
| 抗原种属 | Human |
| 基因ID | 5747 |
| Uniprot ID | |
| 研究领域 | Cardiovascular |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) | purchase Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) | Anti-Phospho-PTK2 (Tyr397) Antibody (5N156) cost | order Anti-Phospho-PTK2 (Tyr397) Antibody (5N156)
嗨！有任何问题？点我咨询
评论内容