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顶部生物活性储存和溶解信息计算器

Anti-ACE Polyclonal Antibody

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Anti-ACE Polyclonal Antibody
产品编号 TMAB-00031
别名 Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme

Anti-ACE Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACE。Anti-ACE Polyclonal Antibody 可用于 WB,ELISA。

Anti-ACE Polyclonal Antibody

Anti-ACE Polyclonal Antibody

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Anti-ACE Polyclonal Antibody
产品编号 TMAB-00031 别名 Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme

Anti-ACE Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACE。Anti-ACE Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-ACE Polyclonal Antibody is a Rabbit antibody targeting ACE. Anti-ACE Polyclonal Antibody can be used in WB,ELISA.
疾病造模方案
别名Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human,Dog,Pig,Cow)
验证活性
Sample:
Lane 1: Mouse Lung tissue lysates
Lane 2: Mouse Testis tissue lysates
Lane 3: Rat Lung tissue lysates
Lane 4: Rat Testis tissue lysates
Primary: Anti-ACE (TMAB-00031) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 147 kDa
Observed band size: 110,180 kDa
应用
WB
ELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Angiotensin-converting enzyme, soluble form: Secreted. Cell membrane; Single-pass type I membrane protein.
组织特异性Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ACE1
抗原种属
Human
基因名称
ACE
基因ID
1636
蛋白名称
Angiotensin-converting enzyme
Uniprot ID
P12821
研究领域
Response to hypoxia,Serum Proteins,Vasoconstriction,ACEs,Cardiovascular ELISA kits,Vitamins / minerals,Hypoxia,Vitamins / Minerals,Surface Molecules
功能
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
化学信息
分子量Theoretical: 147 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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