Anti-AP2 alpha Antibody (5N287) is a Rabbit antibody targeting AP2 alpha. Anti-AP2 alpha Antibody (5N287) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.

IgG

5N287

Human,Mouse,Rat

WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100

Monoclonal

A synthesized peptide: human AP 2 alpha

Human

TFAP2A

Transcription factor AP-2-alpha

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.