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Anti-p53BP1 Antibody (9E596) 是一种 Rabbit 抗体,靶向 p53BP1。Anti-p53BP1 Antibody (9E596) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-p53BP1 Antibody (9E596) 是一种 Rabbit 抗体,靶向 p53BP1。Anti-p53BP1 Antibody (9E596) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-p53BP1 Antibody (9E596) is a Rabbit antibody targeting p53BP1. Anti-p53BP1 Antibody (9E596) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 9E596 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Chromosome; centromere; kinetochore. Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. Methylation of histone H4 at 'Lys-20' is required for efficient localization to double strand breaks. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. |
| 免疫原 | A synthesized peptide: human TP53BP1 |
| 抗原种属 | Human |
| 基因名称 | TP53BP1 |
| 基因ID | |
| 蛋白名称 | TP53-binding protein 1 |
| Uniprot ID | |
| 功能 | May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage. |
| 分子量 | Theoretical: 214 kDa. Actual: 450 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |