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Meclofenoxate hydrochloride

Name: Meclofenoxate hydrochloride
Brand: TargetMol
SKU: T1401
Price: 155 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 97.05%

货号 T1401Cas号 3685-84-5

别名 盐酸甲氯酚酯, 盐酸甲氯芬酯, Meclofenoxate HCl, Meclofenoxate (Centrophenoxine) HCl, Lucidril, Cerutil

Meclofenoxate hydrochloride (Lucidril) 是二甲基氨基乙醇和对氯苯氧乙酸的酯，有刺激记忆和提高认知的活性。

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Meclofenoxate hydrochloride

一键复制产品信息

很棒

纯度: 97.05%

货号 T1401 别名 盐酸甲氯酚酯, 盐酸甲氯芬酯, Meclofenoxate HCl, Meclofenoxate (Centrophenoxine) HCl, Lucidril, CerutilCas号 3685-84-5

Meclofenoxate hydrochloride (Lucidril) 是二甲基氨基乙醇和对氯苯氧乙酸的酯，有刺激记忆和提高认知的活性。

规格	价格	库存
25 mg	¥ 155	现货
50 mg	¥ 223	现货
100 mg	¥ 297	现货
500 mg	¥ 773	现货
1 g	¥ 1,130	现货
1 mL x 10 mM (in DMSO)	¥ 235	现货

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该分子属于定制产品。TargetMol拥有优秀的合成团队，经验和能力，可以为您提供高性价比的产品。如您有任何问题，欢迎咨询，我们将竭诚为您服务。

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纯度: 97.05%

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资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

Meclofenoxate hydrochloride AI Summary

Meclofenoxate hydrochloride exhibits a wide range of bioactivities, including significant potency in inhibiting the proliferation of Plasmodium falciparum, and the expression/activity of various proteins such as Human Peripheral Myelin Protein 22, Bloom's syndrome helicase (BLM), histone lysine methyltransferase G9a, and TGF-b. It also inhibits delayed death in malarial parasites, polymerase Iota, and the entry of Marburg Virus into cells. The compound demonstrates growth inhibition in a variety of human tumor cell lines, including those from breast, lung, renal, colon, melanoma, ovarian, prostate, and leukemia. Additionally, it induces DNA re-replication in normal breast cells and colon adenocarcinoma cells. In OATP1B3 and OATP1B1 transfected CHO cells, Meclofenoxate hydrochloride shows significant inhibition of sodium fluorescein uptake, with inhibition rates of 88.3% and 70.12% at 10 µM, respectively. However, Meclofenoxate hydrochloride shows relatively low bioactivity against SARS-CoV-2, with an inhibition index of 0.1587 in Vero E6 cells and an inhibition rate of -0.03% in VERO-6 cells at 10 µM after 48 hours. It also inhibited SARS-CoV-2 induced cytotoxicity in Caco-2 cells by 18.01% at 10 µM after 48 hours and demonstrated minimal inhibition of the SARS-CoV-2 3CL-Pro protease by 9.156% at 20 µM using a FRET assay..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cognition, and mentally stimulating effect.
别名	盐酸甲氯酚酯, 盐酸甲氯芬酯, Meclofenoxate HCl, Meclofenoxate (Centrophenoxine) HCl, Lucidril, Cerutil

化学信息

分子量	294.17
分子式	C₁₂H₁₆ClNO₃·HCl
CAS No.	3685-84-5
Smiles	c1(ccc(cc1)Cl)OCC(=O)OCCN(C)C.Cl
密度	1.3255 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (203.96 mM), Sonication is recommended.

Ethanol: 54 mg/mL (183.57 mM), Sonication is recommended.

H2O: 53 mg/mL (180.17 mM), Sonication is recommended.

溶液配制表

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3994 mL	16.9970 mL	33.9939 mL	169.9697 mL
5 mM	0.6799 mL	3.3994 mL	6.7988 mL	33.9939 mL
10 mM	0.3399 mL	1.6997 mL	3.3994 mL	16.9970 mL
20 mM	0.1700 mL	0.8498 mL	1.6997 mL	8.4985 mL
50 mM	0.0680 mL	0.3399 mL	0.6799 mL	3.3994 mL
100 mM	0.0340 mL	0.1700 mL	0.3399 mL	1.6997 mL