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Anti-ABP1/AOC1 Antibody (4P152)

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产品编号 TMAY-02609

Anti-ABP1/AOC1 Antibody (4P152) 是一种 Mouse 抗体,靶向 ABP1/AOC1。Anti-ABP1/AOC1 Antibody (4P152) 可用于 ELISA。

Anti-ABP1/AOC1 Antibody (4P152)

Anti-ABP1/AOC1 Antibody (4P152)

Rating icon 还可以
产品编号 TMAY-02609

Anti-ABP1/AOC1 Antibody (4P152) 是一种 Mouse 抗体,靶向 ABP1/AOC1。Anti-ABP1/AOC1 Antibody (4P152) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-ABP1/AOC1 Antibody (4P152) is a Mouse antibody targeting ABP1/AOC1. Anti-ABP1/AOC1 Antibody (4P152) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
4P152
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ABP1/AOC1 (rh ABP1/AOC1; TMPY-00140; AAH14093.1; Met1-Val751). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under control of the proximal AOC1 promoter was significantly enhanced by co-transfection of a WT1 expression construct. Binding of WT1 protein to a cis-regulatory element in the AOC1 promoter was confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. WT1-dependent control of polyamine breakdown, which is mediated by changes in AOC1 expression, has a role in kidney organogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human ABP1/AOC1 Protein (TMPY-00140)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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