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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PSMC2 Antibody (6L860)

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货号 TMAB-11870

Anti-PSMC2 Antibody (6L860) 是一种 Mouse 抗体，靶向 PSMC2。Anti-PSMC2 Antibody (6L860) 可用于 WB。

Anti-PSMC2 Antibody (6L860)

Anti-PSMC2 Antibody (6L860)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11870

Anti-PSMC2 Antibody (6L860) 是一种 Mouse 抗体，靶向 PSMC2。Anti-PSMC2 Antibody (6L860) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-PSMC2 Antibody (6L860) is a Mouse antibody targeting PSMC2. Anti-PSMC2 Antibody (6L860) can be used in WB.
Ig Type
IgG1, k
克隆号
6L860
反应种属
Human (predicted:Mouse,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Co-localizes with TRIM5 in the cytoplasmic bodies.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]
抗原信息
免疫原
Recombinant Protein: human PSMC2
抗原种属
Human
基因名称
PSMC2
基因ID
5701
蛋白名称
26S proteasome regulatory subunit 7
Uniprot ID
P35998
功能
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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