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Anti-Lipocalin-2/LCN2 Antibody (5H677)
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产品编号 TMAH-00684
别名 Siderocalin LCN2, p25, Oncogene 24p3, NGAL, MSFI, Lipocalin-2
Anti-Lipocalin-2/LCN2 Antibody (5H677) 是一种 Mouse 抗体，靶向 Lipocalin-2/LCN2。Anti-Lipocalin-2/LCN2 Antibody (5H677) 可用于 ELISA, WB, IHC。
Anti-Lipocalin-2/LCN2 Antibody (5H677)
Anti-Lipocalin-2/LCN2 Antibody (5H677)
还可以产品编号 TMAH-00684 别名 Siderocalin LCN2, p25, Oncogene 24p3, NGAL, MSFI, Lipocalin-2
Anti-Lipocalin-2/LCN2 Antibody (5H677) 是一种 Mouse 抗体，靶向 Lipocalin-2/LCN2。Anti-Lipocalin-2/LCN2 Antibody (5H677) 可用于 ELISA, WB, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μg | ¥ 1,300 | 5日内发货 | |
| 100 μg | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Lipocalin-2/LCN2 Antibody (5H677) is a Mouse antibody targeting Lipocalin-2/LCN2. Anti-Lipocalin-2/LCN2 Antibody (5H677) can be used in ELISA, WB, IHC. |
| 别名 | Siderocalin LCN2, p25, Oncogene 24p3, NGAL, MSFI, Lipocalin-2 |
| Ig Type | IgG2b |
| 克隆号 | 5H677 |
| 交叉反应 | Human, Mouse |
| 验证活性 | 1. Western Blot -All lanes:Mouse anti-human Neutrophil gelatinase-associated lipocalin monoclonal antibody at 1μg/ml -Lane 1:NGAL transfected 293 cell lysate -Predicted band size : 22 kDa -Observed band size : 25 kDa 2. Immunohistochemical of paraffin-embedded human spleen organization using TMAH-00684 at dilution of 1:200 3. Immunohistochemical of paraffin-embedded human prostate tissue using TMAH-00684 at dilution of 1:200 |
| 应用 | ELISA, WB, IHC |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Secreted. Cytoplasmic granule lumen. Cytoplasmic vesicle lumen. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 纯度 | >95% |
| 研究背景 | Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,3-dihydroxybenzoic acid (2,3-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity; limits bacterial proliferation by sequestering iron bound to microbial siderophores, such as enterobactin. Can also bind siderophores from M.tuberculosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human Neutrophil gelatinase-associated lipocalin Protein |
| 抗原种属 | Human |
| 基因ID | 3934 |
| Uniprot ID | |
| 研究领域 | Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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