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Anti-SEMA4D Antibody (7E489)

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Anti-SEMA4D Antibody (7E489)
产品编号 TMAY-02073
别名 semaphorin 4D, SEMAJ, M-sema-G, coll-4, COLL4, CD100, C9orf164

Anti-SEMA4D Antibody (7E489) 是一种 Mouse 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (7E489) 可用于 FCM。

Anti-SEMA4D Antibody (7E489)

Anti-SEMA4D Antibody (7E489)

Rating icon 还可以
Anti-SEMA4D Antibody (7E489)
产品编号 TMAY-02073 别名 semaphorin 4D, SEMAJ, M-sema-G, coll-4, COLL4, CD100, C9orf164

Anti-SEMA4D Antibody (7E489) 是一种 Mouse 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (7E489) 可用于 FCM。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-SEMA4D Antibody (7E489) is a Mouse antibody targeting SEMA4D. Anti-SEMA4D Antibody (7E489) can be used in FCM.
别名semaphorin 4D, SEMAJ, M-sema-G, coll-4, COLL4, CD100, C9orf164
Ig Type
Mouse IgG1
克隆号
7E489
交叉反应
Human
验证活性
Flow cytometric analysis of Human SEMA4D(CD100) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human SEMA4D(CD100), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Semaphorin 4D / SEMA4D / CD100 (rh Semaphorin 4D / SEMA4D / CD100; TMPY-01906; AAH54500.1; Met1-Arg734). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
PE
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human Semaphorin 4D / SEMA4D / CD100 Protein (TMPY-01906)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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