购物车
- 全部删除
您的购物车当前为空
Anti-PFKFB3 Antibody (1B165)
还可以
产品编号 TMAC-03170
别名 PFK2, PFK/FBPase 3, iPFK-2, IPFK2
Anti-PFKFB3 Antibody (1B165) 是一种 Rabbit 抗体，靶向 PFKFB3。Anti-PFKFB3 Antibody (1B165) 可用于 WB,ICC,IHC,FCM,IP。
Anti-PFKFB3 Antibody (1B165)
Anti-PFKFB3 Antibody (1B165)
还可以产品编号 TMAC-03170 别名 PFK2, PFK/FBPase 3, iPFK-2, IPFK2
Anti-PFKFB3 Antibody (1B165) 是一种 Rabbit 抗体，靶向 PFKFB3。Anti-PFKFB3 Antibody (1B165) 可用于 WB,ICC,IHC,FCM,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PFKFB3 Antibody (1B165) is a Rabbit antibody targeting PFKFB3. Anti-PFKFB3 Antibody (1B165) can be used in WB,ICC,IHC,FCM,IP. |
| 别名 | PFK2, PFK/FBPase 3, iPFK-2, IPFK2 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of PFKFB3 on different cell lysates using anti-PFKFB3 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: PC-12, Lane 3: A431. 2. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-PFKFB3 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PFKFB3 antibody. Counter stained with hematoxylin. 4. ICC staining PFKFB3 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining PFKFB3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of A431 cells with PFKFB3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Among the enzymes playing role in glycolysis,four allosteric PFKFB enzymes 1?C4 expressed by four independent PFKFB genes, catalyze the rate-limiting phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate, using ATP as the energy source in the glycolysis pathway. Among these four allosteric enzymes, PFKFB3 enzyme retains the highest Kinase/Biphosphatase activity ratio and is expressed by PFKFB3 gene which has been demonstrated to be highly expressed in leukemic cells and in solid tumors. Moreover, mitogenic, hypoxic and inflammatory conditions have an inductive effect on the expression of PFKFB3. Hence upregulation of PFKFB genes specific to cancer cells compared to their normal counterparts (from the same patients) with more robust over-expression in breast and lung cancer make it a more appropriate target. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-PFKFB3 Antibody (1B165) | purchase Anti-PFKFB3 Antibody (1B165) | Anti-PFKFB3 Antibody (1B165) cost | order Anti-PFKFB3 Antibody (1B165)
嗨！有任何问题？点我咨询
评论内容