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Anti-Phospho-RPS6KA5 (S376) Antibody (8P256) 是一种 Rabbit 抗体,靶向 Phospho-RPS6KA5 (S376)。Anti-Phospho-RPS6KA5 (S376) Antibody (8P256) 可用于 WB,ICC,IHC,IP。
Anti-Phospho-RPS6KA5 (S376) Antibody (8P256) 是一种 Rabbit 抗体,靶向 Phospho-RPS6KA5 (S376)。Anti-Phospho-RPS6KA5 (S376) Antibody (8P256) 可用于 WB,ICC,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Phospho-RPS6KA5 (Ser376) Antibody (8P256) 是一种 Rabbit 抗体,靶向 Phospho-RPS6KA5 (Ser376)。Anti-Phospho-RPS6KA5 (Ser376) Antibody (8P256) 可用于 WB,ICC,IHC,IP。 |
别名 | S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RPS6KA5 (p-Ser376), RPS6KA5 (p-S376), RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, p-RPS6KA5 (Ser376), p-RPS6KA5 (S376), Phospho-RPS6KA5 (S376), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5 |
Ig Type | IgG |
交叉反应 | Human,Rat |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded mouse bladder tissue using anti-MSK1 (phospho S376) antibody. Counter stained with hematoxylin. 2. ICC staining MSK1(phospho S376) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining MSK1(phospho S376) in LO2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining MSK1(phospho S376) in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining MSK1(phospho S376) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, have been implicated as important signaling intermediates in response to a broad range of ligand-activated receptor tyrosine kinases. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. A related S6 kinase, p70 S6 kinase, functions to phosphorylate the S6 protein on ribosomal 40S subunits. p70 S6 kinase b shares high sequence homology with p70 S6 kinase, except in the carboxy terminus where it contains a proline-rich domain that may be involved in SH3 domain containing protein interactions. MSK1 (also designated RLPK) is related to Rsk and p70 S6 kinase family members and is thought to be structurally similar to Rsk family members, but it may be regulated by distinct mechanisms. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human MSK1 around the phosphorylation site of Ser376 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 90/80 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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