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顶部生物活性储存和溶解信息计算器

Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody

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Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody
产品编号 TMAC-03957
别名 Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, TGF1a, TGF beta activated kinase 1, TAK1 (p-Thr184), TAK1 (p-T184), TAK1, p-TAK1 (Thr184), p-TAK1 (T184), Mitogen-activated protein kinase kinase kinase 7, MEKK7, MAPKKK7, MAP3K7, Map3k7, MAP3K 7, M3K7

Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-TAK1 (Thr184)。Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody 可用于 WB。

Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody

Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody
产品编号 TMAC-03957 别名 Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, TGF1a, TGF beta activated kinase 1, TAK1 (p-Thr184), TAK1 (p-T184), TAK1, p-TAK1 (Thr184), p-TAK1 (T184), Mitogen-activated protein kinase kinase kinase 7, MEKK7, MAPKKK7, MAP3K7, Map3k7, MAP3K 7, M3K7

Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-TAK1 (Thr184)。Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TAK1 (Thr184). Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody can be used in WB.
别名Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, TGF1a, TGF beta activated kinase 1, TAK1 (p-Thr184), TAK1 (p-T184), TAK1, p-TAK1 (Thr184), p-TAK1 (T184), Mitogen-activated protein kinase kinase kinase 7, MEKK7, MAPKKK7, MAP3K7, Map3k7, MAP3K 7, M3K7
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HepG2 cells, treated with TNF (20ng/ml, 5mins), using TAK1 (Phospho-Thr184) antibody TMAC-03957. The lane on the right is treated with the synthesized peptide.
2. Western blot analysis of extracts from 293 cells (Lane 2), using TAK1 (Phospho-Thr184) Antibody TMAC-03957. The lane on the left is treated with synthesized peptide.
应用
WB
推荐剂量
WB: 1:500-3000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine 184 (I-Q-T(p)-H-M) derived from Human TAK1
抗原种属
human
Uniprot ID
O43318
化学信息
分子量Actual: 65 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

TAK1 (pThr184)TAK1 (pT184)TAK1 (phospho-Thr184)TAK1 (phospho-T184)pTAK1 (Thr184)pTAK1 (T184)

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