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Anti-CYCS Antibody (7T202)

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货号 TMAC-01068

别名 Cytochrome C, CYCS, CYC

Anti-CYCS Antibody (7T202) 是一种 Rabbit 抗体,靶向 CYCS。Anti-CYCS Antibody (7T202) 可用于 ICC/IF,IHC,IP,WB。

Anti-CYCS Antibody (7T202)

Anti-CYCS Antibody (7T202)

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货号 TMAC-01068 别名 Cytochrome C, CYCS, CYC

Anti-CYCS Antibody (7T202) 是一种 Rabbit 抗体,靶向 CYCS。Anti-CYCS Antibody (7T202) 可用于 ICC/IF,IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-CYCS Antibody (7T202) is a Rabbit antibody targeting CYCS. Anti-CYCS Antibody (7T202) can be used in ICC/IF,IHC,IP,WB.
别名Cytochrome C, CYCS, CYC
Ig Type
IgG
克隆号
7T202
反应种属
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
5. ICC staining Cytochrome C in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用ICC/IFIHCIPWB
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cytochrome c is a well characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial intermembrane space. More recent studies have identifed cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is translocated from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 14 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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