Anti-CD6 Antibody (7P764)

Name: Anti-CD6 Antibody (7P764)
Brand: TargetMol
SKU: TMAY-03422
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03422

Anti-CD6 Antibody (7P764) 是一种 Rabbit 抗体，靶向 CD6。Anti-CD6 Antibody (7P764) 可用于 ICC/IF。

Anti-CD6 Antibody (7P764)

还可以

产品编号 TMAY-03422

Anti-CD6 Antibody (7P764) 是一种 Rabbit 抗体，靶向 CD6。Anti-CD6 Antibody (7P764) 可用于 ICC/IF。

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生物活性

产品描述	Anti-CD6 Antibody (7P764) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (7P764) can be used in ICC/IF.
Ig Type	Monoclonal Rabbit IgG
克隆号	7P764
交叉反应	Mouse
验证活性	Immunofluorescence staining of mouse CD6 in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse CD6 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green).
应用	ICC/IF
推荐剂量	ICC-IF: 1:20-1:100
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 / Cluster of Differentiation 6 (rM CD6 / Cluster of Differentiation 6; TMPY-02254; Q91WN5; Met1-Gly396).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse CD6 / Cluster of Differentiation 6 protein (TMPY-02254)
抗原种属	Mouse
研究领域	ITIM/ITAM Immunoreceptors and Related Molecules

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.