Anti-FOS Antibody (6V247) is a Rabbit antibody targeting FOS. Anti-FOS Antibody (6V247) can be used in FCM.

IgG

6V247

Human (predicted:Mouse,Rat)

The Hela （treated with 200 nM PMA for 4 hours)(H) cells were fixed with 4% PFA (10 min at room temperature) and then permeabilized with 90% ice-cold methanol for 20 min at-20°C,the cells then were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at room temperature). Primary Antibody (green): Rabbit Anti-c-Fos antibody (TMAB-00701): 1 μg/10^6 cells; Secondary Antibody (white blue): Goat anti-Rabbit IgG-FITC: 1 μg/test. Isotype Control (orange): Rabbit IgG. Blank control (black): PBS.

FCM: 1ug/Test

Monoclonal

Recombinant Protein: human c-Fos protein (50-200aa)

Human

FOS

Proto-oncogene c-Fos

Transcription factors,Oncoproteins,Proto-oncogenes,Leucine Zipper,Soma marker

Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.