Name: DcR1/TRAILR3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04722
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 243

3日内发货

10 μg

¥ 378

3日内发货

20 μg

¥ 593

3日内发货

50 μg

¥ 1,170

3日内发货

100 μg

¥ 1,960

现货

生物活性

产品描述	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
生物活性	1.Measured by its binding ability in a functional ELISA. 2. Immobilized human TNFRSF10C at 10μg/mL (100μL/well) can bind biotinylated human TNFSF10 (10409-HNAE), the EC50 of biotinylated human TNFSF10 is 0.1-0.7μg/mL.
研究背景	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	O14798
蛋白构建	A DNA sequence encoding the human TNFRSF10C (NP_003832.2) (Met1-Pro235) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 26
蛋白纯度	> 95 % as determined by SDS-PAGE.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	tumor necrosis factor receptor superfamily member 10c, TRID, TRAIL-R3, TRAILR3, LIT, DCR1-TNFR, DCR1, CD263
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.