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别名 RNF55, Proto-oncogene c-Cbl, p-CBL (Y700), p-CBL (Tyr700), CBL2, CBL (p-Y700), CBL (p-Tyr700)
Anti-Phospho-CBL (Tyr700) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CBL (Tyr700)。Anti-Phospho-CBL (Tyr700) Polyclonal Antibody 可用于 IF,IHC,WB。
Anti-Phospho-CBL (Tyr700) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CBL (Tyr700)。Anti-Phospho-CBL (Tyr700) Polyclonal Antibody 可用于 IF,IHC,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,235 | 5日内发货 |
| 产品描述 | Anti-Phospho-CBL (Tyr700) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CBL (Tyr700). Anti-Phospho-CBL (Tyr700) Polyclonal Antibody can be used in IF,IHC,WB. |
| 别名 | RNF55, Proto-oncogene c-Cbl, p-CBL (Y700), p-CBL (Tyr700), CBL2, CBL (p-Y700), CBL (p-Tyr700) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of extracts from HT29 cells untreated or treated with UV using c-Cbl (phospho-Tyr700) Antibody TMAC-00638. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Cbl (Phospho-Tyr700) Antibody TMAC-00638(left) or the same antibody preincubated with blocking peptide (right). 3. Immunofluorescence staining of methanol-fixed Hela cells using c-Cbl (phospho-Tyr700) Antibody TMAC-00638. ![]() ![]() ![]() |
| 应用 | IFIHCWB |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of tyrosine 770 (T-E-Y(p)-M-T) derived from Human c-Cbl |
| 抗原种属 | human |
| Uniprot ID |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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