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Anti-IL-13RA2 Antibody (6J715) 是一种 Rabbit 抗体,靶向 IL-13RA2。Anti-IL-13RA2 Antibody (6J715) 可用于 ELISA。
Anti-IL-13RA2 Antibody (6J715) 是一种 Rabbit 抗体,靶向 IL-13RA2。Anti-IL-13RA2 Antibody (6J715) 可用于 ELISA。
产品描述 | Anti-IL-13RA2 Antibody (6J715) is a Rabbit antibody targeting IL-13RA2. Anti-IL-13RA2 Antibody (6J715) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6J715 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL13RA2 (NP_032382.1Met 1-Lys 334). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High-Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse IL13RA2 protein |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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