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Anti-MAP1A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAP1A。Anti-MAP1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-MAP1A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAP1A。Anti-MAP1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-MAP1A Polyclonal Antibody is a Rabbit antibody targeting MAP1A. Anti-MAP1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. |
| 组织特异性 | Most abundant in placenta, lung and ovary. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. There are three isoforms of human LC3 (named MAP1LC3A, MAP1LC3B, and MAP1LC3C), which exhibit different tissue distributions. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy. |
| 免疫原 | KLH conjugated synthetic peptide: human MAP1A heavy chain |
| 抗原种属 | Human |
| 基因名称 | MAP1LC3C |
| 基因ID | |
| 蛋白名称 | Microtubule-associated proteins 1A/1B light chain 3C |
| Uniprot ID | |
| 功能 | Probably involved in formation of autophagosomal vacuoles (autophagosomes). |
| 分子量 | Theoretical: 326 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |