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Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

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货号 TMPK-00149

别名 Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a

Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.

Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
其他形式的 “Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)”:
CD64 Protein, Human, Recombinant (His & Avi)
CD64 Protein, Human, Recombinant (His & Avi), Biotinylated
Fc epsilon RI Protein, Human, Recombinant (His)
Fc epsilon RI Protein, Mouse, Recombinant (hFc)
Fc epsilon RI Protein, Human, Recombinant

Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00149 别名 Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a

Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.

规格价格库存数量
5 μg
¥ 246
6-8日内发货
10 μg
¥ 383
6-8日内发货
20 μg
¥ 616
5日内发货
50 μg
¥ 1,190
5日内发货
100 μg
¥ 1,990
5日内发货
200 μg
¥ 3,590
5日内发货
500 μg
¥ 8,000
5日内发货
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产品介绍

生物活性
产品描述
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.
生物活性
Immobilized Human Fc epsilon RI alpha, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Fc epsilon RI alpha Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
研究背景
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号P12319-1
蛋白构建Val26-Gln205
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量22.1 kDa (predicted). Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

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