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Anti-IL-17RA Antibody (3M821)
还可以产品编号 TMAY-01301
Anti-IL-17RA Antibody (3M821) 是一种 Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody (3M821) 可用于 WB,ELISA,ELISA(Cap)。
Anti-IL-17RA Antibody (3M821)
Anti-IL-17RA Antibody (3M821)
还可以产品编号 TMAY-01301
Anti-IL-17RA Antibody (3M821) 是一种 Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody (3M821) 可用于 WB,ELISA,ELISA(Cap)。
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| 产品描述 | Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in WB,ELISA,ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3M821 |
| 交叉反应 | Human |
| 验证活性 | Anti-IL17RA mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:96 kDa. -Observed band size:105 kDa(We are unsure as to the identity of these extra bands.) |
| 应用 | WB,ELISA,ELISA(Cap) |
| 推荐剂量 | WB: 1:500-1:1000; ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA (rh IL17RA; TMPY-01371; NP_055154.3; Met 1-Trp 320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL17RA protein (TMPY-01371) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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