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DEFB4A Protein, Human, Recombinant

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货号 TMPJ-00667

别名 β-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2

β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.

DEFB4A Protein, Human, Recombinant

DEFB4A Protein, Human, Recombinant

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Rating icon 很棒
SPR兼容缓冲液
货号 TMPJ-00667 别名 β-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2

β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.

规格价格库存数量
5 μg
¥ 385
现货
10 μg
¥ 620
现货
20 μg
¥ 958
2-4周
50 μg
¥ 1,730
2-4周
100 μg
¥ 2,970
2-4周
200 μg
¥ 5,550
2-4周
500 μg
¥ 12,100
2-4周
1 mg
¥ 17,300
2-4周
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纯度: Greater than 95% as determined by reducing SDS-PAGE.
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产品介绍


生物活性
产品描述
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号O15263
氨基酸序列Gly24-Pro64
蛋白构建Gly24-Pro64
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名β-Defensin 4A, β-Defensin 2, β2, Skin-Antimicrobial Peptide 1, SAP1, hBD-2, Defensin, DEFB4B, DEFB4A, DEFB4, DEFB2, DEFB102, Beta-Defensin 4A, Beta-Defensin 2, Beta 2, BD-2
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量9 KDa (reducing condition)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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