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Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)

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Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
产品编号 TMAY-01688
别名 p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118)

Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 是一种 Rabbit 抗体,靶向 Phospho-Paxillin (Tyr118)。Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 可用于 WB。

Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
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Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)

Rating icon 还可以
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
产品编号 TMAY-01688 别名 p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118)

Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 是一种 Rabbit 抗体,靶向 Phospho-Paxillin (Tyr118)。Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 可用于 WB。

规格价格库存数量
20 μL
¥ 684
5日内发货
100 μL
¥ 1,989
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) is a Rabbit antibody targeting Phospho-Paxillin (Tyr118). Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) can be used in WB.
别名p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118)
Ig Type
Rabbit IgG
克隆号
8M93
交叉反应
Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Cyomolgus
验证活性
1. Western blot analysis of extracts from A-431, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Paxillin (Tyr118) Antibody, Rabbit MAb at 1:1000 dilution.
2. Western blot analysis of extracts from A-431 using Phospho-Paxillin (Tyr118) rabbit monoclonal Antibody at dilution of 1:2000, 1:10000 and 1:50000.
应用
WB
推荐剂量
WB: 1:1000-1:5000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景PXN was significantly upregulated in cervical cancer, which associated with tumor stage, poor differentiation, lymphovascular space invasion and lymphatic metastasis. Knockdown of PXN notably impaired cellular growth and colony formation by suppressing Bcl-2 and inducing marked apoptosis. Moreover, PXN led to resistance to radiation, and downregulation of PXN resensitized C33A cells to radiation.PXN was frequently upregulated and acted as an oncogene via regulating Bcl-2 in cervical cancer, which supports PXN as a potent therapeutic target.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: residues around Tyr118 of the Human Phospho-Paxillin
抗原种属
Human
研究领域
Adaptor Proteins
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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