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Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
还可以产品编号 TMAY-01688
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 是一种 Rabbit 抗体，靶向 Phospho-Paxillin (Tyr118)。Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 可用于 WB。
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
还可以产品编号 TMAY-01688
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 是一种 Rabbit 抗体，靶向 Phospho-Paxillin (Tyr118)。Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) is a Rabbit antibody targeting Phospho-Paxillin (Tyr118). Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8M93 |
| 交叉反应 | Human; Predicted to React with:Species predicted to react based on 100% sequence homology: Cyomolgus |
| 验证活性 | 1. Western blot analysis of extracts from A-431, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Paxillin (Tyr118) Antibody, Rabbit MAb at 1:1000 dilution. 2. Western blot analysis of extracts from A-431 using Phospho-Paxillin (Tyr118) rabbit monoclonal Antibody at dilution of 1:2000, 1:10000 and 1:50000. |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-1:5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | PXN was significantly upregulated in cervical cancer, which associated with tumor stage, poor differentiation, lymphovascular space invasion and lymphatic metastasis. Knockdown of PXN notably impaired cellular growth and colony formation by suppressing Bcl-2 and inducing marked apoptosis. Moreover, PXN led to resistance to radiation, and downregulation of PXN resensitized C33A cells to radiation.PXN was frequently upregulated and acted as an oncogene via regulating Bcl-2 in cervical cancer, which supports PXN as a potent therapeutic target. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin |
| 抗原种属 | Human |
| 研究领域 | Adaptor Proteins |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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