LILRA3/CD85e Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAH28208.1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 2,440 | 5日内发货 | ||
100 μg | ¥ 5,810 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | LILRA3/CD85e Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAH28208.1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | AAH28208.1 |
别名 | LIR4, ILT-6, HM31, leukocyte immunoglobulin like receptor A3, ILT6, HM43, CD85e, LIR-4 |
蛋白构建 | The Human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro. |
蛋白纯度 | > 85 % as determined by SDS-PAGE |
分子量 | 46.5 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease. |
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LILRA3/CD85e Protein, Human, Recombinant (His), Biotinylated LIR4 ILT-6 HM31 HM 43 leukocyte immunoglobulin like receptor A3 ILT6 HM43 HM-43 HM 31 LIR 4 CD85e ILT 6 HM-31 LIR-4 recombinant recombinant-proteins proteins protein