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Anti-CDV Fusion glycoprotein F0 Antibody (4S488) 是一种 Mouse 抗体,靶向 CDV Fusion glycoprotein F0。Anti-CDV Fusion glycoprotein F0 Antibody (4S488) 可用于 WB,ELISA。
Anti-CDV Fusion glycoprotein F0 Antibody (4S488) 是一种 Mouse 抗体,靶向 CDV Fusion glycoprotein F0。Anti-CDV Fusion glycoprotein F0 Antibody (4S488) 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 200 μg | ¥ 5,595 | 5日内发货 | |
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-CDV Fusion glycoprotein F0 Antibody (4S488) is a Mouse antibody targeting CDV Fusion glycoprotein F0. Anti-CDV Fusion glycoprotein F0 Antibody (4S488) can be used in WB,ELISA. |
| Ig Type | IgG |
| 克隆号 | 4S488 |
| 反应种属 | CDV |
| 应用 | WBELISA |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis |
| 免疫原 | Recombinant Protein: Canine distemper virus Fusion glycoprotein F0 |
| 基因名称 | F |
| 蛋白名称 | Fusion glycoprotein F0 |
| 分子量 | Theoretical: 73 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |