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Anti-Elafin Antibody (7F242)
还可以产品编号 TMAY-02271
Anti-Elafin Antibody (7F242) 是一种 Rabbit 抗体，靶向 Elafin。Anti-Elafin Antibody (7F242) 可用于 ELISA。
Anti-Elafin Antibody (7F242)
Anti-Elafin Antibody (7F242)
还可以产品编号 TMAY-02271
Anti-Elafin Antibody (7F242) 是一种 Rabbit 抗体，靶向 Elafin。Anti-Elafin Antibody (7F242) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7F242 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PI3 / Elafin / WFDC14 (rh PI3 / Elafin / WFDC14; TMPY-01909; NP_002629.1; Met1-Gln117). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. The serine anti-protease Elafin / PI3 is expressed by monocytes, alveolar macrophages, neutrophils, and at mucosal surfaces and possesses antimicrobial activity. It is also known to reduce lipopolysaccharide-induced neutrophil influx into murine alveoli as well as to abrogate lipopolysaccharide-induced production of matrix metalloprotease 9, macrophage inhibitory protein 2, and tumor necrosis factor-alpha by as-yet unidentified mechanisms. Elafin / PI3 is a neutrophil serine protease inhibitor expressed in lung and displaying anti-inflammatory and anti-bacterial properties. Elafin / PI3 is a neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Elafin / PI3 will regulate proteolytic enzymes during menstruation and will contribute to the innate defense against uterine infection. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PI3 / Elafin / WFDC14 protein (TMPY-01909) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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