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Anti-Elafin Antibody (7F242)

Synonyms: WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin
货号 TMAY-02271 一键复制产品信息
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202603开学季活动

Anti-Elafin Antibody (7F242) 是一种 Rabbit 抗体,靶向 Elafin。Anti-Elafin Antibody (7F242) 可用于 ELISA。

Anti-Elafin Antibody (7F242)

一键复制产品信息
Rating icon 还可以
202603开学季活动
货号 TMAY-02271

别名 WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin

Anti-Elafin Antibody (7F242) 是一种 Rabbit 抗体,靶向 Elafin。Anti-Elafin Antibody (7F242) 可用于 ELISA。

Anti-Elafin Antibody (7F242)
规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍


生物活性
产品描述
Anti-Elafin Antibody (7F242) is a Rabbit antibody targeting Elafin. Anti-Elafin Antibody (7F242) can be used in ELISA.
别名
WFDC14, WAP3, SKALP, peptidase inhibitor 3, MGC13613, ESI, cementoin
Ig Type
Rabbit IgG
克隆号
7F242
反应种属
Human
特异性
Human Elafin
No cross-reactivity in ELISA with
Human SLPI
Human TGM2
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human PI3 / Elafin / WFDC14 (rh PI3 / Elafin / WFDC14; TMPY-01909; NP_002629.1; Met1-Gln117).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. The serine anti-protease Elafin / PI3 is expressed by monocytes, alveolar macrophages, neutrophils, and at mucosal surfaces and possesses antimicrobial activity. It is also known to reduce lipopolysaccharide-induced neutrophil influx into murine alveoli as well as to abrogate lipopolysaccharide-induced production of matrix metalloprotease 9, macrophage inhibitory protein 2, and tumor necrosis factor-alpha by as-yet unidentified mechanisms. Elafin / PI3 is a neutrophil serine protease inhibitor expressed in lung and displaying anti-inflammatory and anti-bacterial properties. Elafin / PI3 is a neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Elafin / PI3 will regulate proteolytic enzymes during menstruation and will contribute to the innate defense against uterine infection.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PI3 / Elafin / WFDC14 protein (TMPY-01909)
抗原种属
Human
研究领域
Serine Proteases and Regulators
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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