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Anti-SIGNR1 Antibody (2W828)
还可以产品编号 TMAY-03317
Anti-SIGNR1 Antibody (2W828) 是一种 Rabbit 抗体，靶向 SIGNR1。Anti-SIGNR1 Antibody (2W828) 可用于 ICC/IF。
Anti-SIGNR1 Antibody (2W828)
Anti-SIGNR1 Antibody (2W828)
还可以产品编号 TMAY-03317
Anti-SIGNR1 Antibody (2W828) 是一种 Rabbit 抗体，靶向 SIGNR1。Anti-SIGNR1 Antibody (2W828) 可用于 ICC/IF。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-SIGNR1 Antibody (2W828) is a Rabbit antibody targeting SIGNR1. Anti-SIGNR1 Antibody (2W828) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2W828 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Immunofluorescence staining of mouse CD209B in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse CD209B monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). 2. Flow cytometric analysis of Mouse CD209b expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse CD209b, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SIGNR1 / CD209b (rM SIGNR1 / CD209b; TMPY-01733; NP_081248.2; Gln74-Gly325). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD209b, also known as SIGNR1, is a C-type lectin receptor. CD209b is present on most regions of mouse brain and found on microglia and dendritic cells but not on neurons or astrocytes. CD209b is implicated in the recently described SIGNR1 complement activation pathway, which operates against capsular polysaccharides in splenic marginal macrophages. CD209b in rat is homologue to SIGNR1 in mouse, both of which are found to mediate the uptake of dextran or CPS14 within the splenic marginal zone. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse SIGNR1 / CD209b protein (TMPY-01733) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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