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别名 Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1
Anti-FBPase1 Antibody (6B758) 是一种抗体,靶向 FBPase1。Anti-FBPase1 Antibody (6B758) 可用于 ELISA,IHC。
Anti-FBPase1 Antibody (6B758) 是一种抗体,靶向 FBPase1。Anti-FBPase1 Antibody (6B758) 可用于 ELISA,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
| 产品描述 | Anti-FBPase1 Antibody (6B758) is an antibody targeting FBPase1. Anti-FBPase1 Antibody (6B758) can be used in ELISA,IHC. |
| 别名 | Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 6B758 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00421 diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISAIHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 组织特异性 | Expressed in pancreatic islets. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human FBP1 |
| 抗原种属 | Human |
| 基因名称 | FBP1 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cancer, Metabolism, Signal transduction |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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